Hydrabio Mask can be used once or twice a day, every day during the first week of application for optimal results, then as a follow-up once or twice a week. Start by cleansing your face and neck with a product from our Hydrabio line. Apply Hydrabio Tonic Lotion if needed. Apply a thick layer of Hydrabio Mask. Leave it on for 10 minutes, before removing excess product with a cotton pad.